Search results for "Strongyloides stercoralis"
showing 10 items of 11 documents
Pulmonary Strongyloides stercoralis infection.
2016
Association between urticaria and nematode infections
2018
Background The association between parasites and urticaria was first suggested in the last century. A wide range, 0-75.4%, of the prevalence of parasitic infection has been reported with chronic urticaria (CU). Moreover, urticaria may be detected in patients with parasitosis. Nematodes are a type of helminth that infect hundreds of millions of people throughout the world. Objective The aim of this work was to collect and review the published studies and cases of urticaria associated with nematode infections. Methods A search of scientific literature data bases from January 1960 until May 2017 was carried out. Results Numerous nematode infections have been associated with urticaria and/or an…
A Strongyloides stercoralis infection presenting as arthritis of sternoclavicular joint
2016
Strongyloides stercoralis (S. stercoralis) is a parasite, endemic in tropical, subtropical, and also not rarely in temperate regions, that infects up to 100 million people worldwide [1]. Patients m...
Eosinophil-selective mediators in human strongyloidiasis
2006
SUMMARY Strongyloides stercoralis infection is characterized by the production of IgE and eosinophils in peripheral blood. Experimental studies have demonstrated that eosinophils play an important role in protection against Strongyloides stercoralis, but the mechanisms regulating eosinophils are not known. In this study we have focused on analysing the molecules that selectively regulate eosinophil migration, namely eotaxin and interleukin-5 (IL-5), using an enzyme-linked immunosorbent assay in patients with strongyloidiasis. Serum expression of eotaxin and IL-5 were significantly increased in patients compared with the control group. This rise suggests that selective mediators of the eosin…
Strongyloidiasis in northern Vietnam: epidemiology, clinical characteristics and molecular diagnosis of the causal agent.
2019
Abstract Background Strongyloidiasis is a health problem in Vietnam, but appropriate information is still limited. The aim of this study was to determine the prevalence, geographical distribution, epidemiological aspects, symptoms and other health indicators of Strongyloides stercoralis infections in patients from 27 provinces of northern Vietnam attending the Hanoi Medical University Hospital during 2016 and 2017. Methods Blood samples of 2000 patients were analyzed for S. stercoralis infection with an IgG ELISA test. Seroprevalence was analyzed by gender, age group, locality of origin (rural or urban areas) and symptoms. Stools from the seropositive patients were examined for the detectio…
Donor-derived Strongyloides stercoralis hyperinfection syndrome after simultaneous kidney/pancreas transplantation
2016
Most cases of strongyloidiasis associated with solid organ transplantation have been due to the reactivation of a latent infection in the recipient as a result of the immunosuppressive therapy; however, donor-derived infections are becoming increasingly frequent. The case of a patient who nearly died of a Strongyloides stercoralis hyperinfection after receiving simultaneous kidney/pancreas transplants is described herein. No specific parasitological tests were performed pre-transplantation, despite the fact that both the recipient and the donor originated from endemic areas. Serological analysis of the donor's serum performed retrospectively revealed the origin of the infection, which if it…
Proteomic analysis of Strongyloides stercoralis L3 larvae
2010
SUMMARYStrongyloidiasis can be perpetuated by autoinfection with the filariform larvae L3, causing asymptomatic chronic infections and creating a population of carriers, affecting not only developing countries. So far, very little is known about the proteins that interact with the human host, and few proteins from the infective Strongyloides stercoralis L3 have been characterized. Here, we report results obtained from a proteomic analysis of the proteins from S. stercoralis L3 larvae obtained from patients. Since the genome of S. stercoralis is not yet available, we used proteomic analysis to identify 26 different proteins, 13 of them released by short digestion with trypsin, which could re…
Identificación y caracterización de proteínas de Strongyloides stercoralis de utilidad para el diagnóstico y control de la enfermedad mediante técnic…
2016
El nematodo Strongyloides stercoralis es el principal causante de la estrongiloidiasis humana. Debido a la capacidad del parásito de perpetuar un ciclo autoinfectivo la infección puede prolongarse durante años en el hospedador, dando lugar a una enfermedad crónica en personas inmunocompetentes, mientras que en condiciones de inmunosupresión puede desembocar en cuadros clínicos graves con elevadas tasas de mortalidad. La región de La Safor valenciana ha sido considerada foco endémico de este parásito desde hace más de un siglo, habiéndose diagnosticado cientos de casos desde entonces, suponiendo un problema sanitario en la región. La presente Tesis contribuye a la mejora en el conocimiento p…
The transcriptome analysis of Strongyloides stercoralis L3i larvae reveals targets for intervention in a neglected disease.
2012
Background: Strongyloidiasis is one of the most neglected diseases distributed worldwide with endemic areas in developed countries, where chronic infections are life threatening. Despite its impact, very little is known about the molecular biology of the parasite involved and its interplay with its hosts. Next generation sequencing technologies now provide unique opportunities to rapidly address these questions. Principal Findings: Here we present the first transcriptome of the third larval stage of S. stercoralis using 454 sequencing coupled with semi-automated bioinformatic analyses. 253,266 raw sequence reads were assembled into 11,250 contiguous sequences, most of which were novel. 8037…
Hiperinfección por Strongyloides stercoralis
2010
El Strongyloides stercoralis (Ss) es un nematodo endémico en países de clima tropical y subtropical, y en España se han descrito casos, sobre todo en la costa mediterránea. La infección por Ss suele ser asintomática o manifestarse por síntomas predominantemente digestivos, y en los casos de hiperinfestación produce una estrongiloidiasis diseminada con sobreinfecciones bacterianas sistémicas que provocan una disfunción multiorgánica con resultado letal. Los factores de riesgo más importantes para que una infección en principio intestinal y en muchas ocasiones asintomática adquiera características de gravedad son la inmunosupresión y la utilización de corticoides, por su capacidad de alterar …